Chronic Lymphocytic Leukemia

​• The role of BTK monotherapy
• Bcl-2 inhibitor combinations
• Biology and clonal evolution of CLL
• Cellular therapies for CLL
• Monoclonals and bispecifics in CLL
• Novel approaches to Richter’s  
  transformation

CLL

Huang et al., Front Cell Dev Biol. 2021

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Ocana et al., Oncotarget. 2017

Multiple Myeloma

• Smoldering myeloma and special populations
• T-cell engagers in MM
• CAR-T for MM
• Predictive biomarkers and precision therapy

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Brentjens and Curran. Hematology Am Soc Hematol Educ Program. 2017

mm

Van de Donk et al., Lancet Oncol. 2021

mm2

Lymphoma

• Chemo-free therapy for DLBCL
• Peripheral T-cell lymphoma
• Mantle cell lymphoma
• Marginal zone lymphoma
• Waldenström macroglobulinemia
• Follicular lymphoma
• Hodgkin Lymphoma
• Uncommon lymphoma subtypes
• Bispecifics as monotherapy in B-cell
   lymphoma
• Combination therapy for B-cell lymphoma

lymphoma

Mihalyova et al., Int J Mol Sci. 2021

lymphoma2

Leukemia and MDS/MPN

• Acute myeloid leukemia
• Acute lymphoblastic leukemia
• Translational biology of AML, MDS,
   and MPN
• Molecularly targeted therapies for AML,
   ALL, and MPN
• Myelofibrosis
• Mastocytosis
• Hairy cell leukemia
• Chronic neutrophilic leukemia
• Large granular lymphocyte leukemia

leukemia

Gurney and O’Dwyer, Cancers. 2021

leukemia2

Figure 1. Myeloproliferative neoplasms and myelodysplastic syndromes.

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Figure 2. A schematic description of genotypic diversity in patients with myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN).

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Mullighan, Nat Genet. 2009

DAVA Oncology

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